Taipei, Taiwan – BIO Asia-Taiwan 2025 successfully concluded on July 24–27 at Nangang
Exhibition Center Hall 1. Among the highlights of the exhibition was the research team led by
Prof. Yuh-Shyong Yang from National Yang Ming Chiao Tung University (NYCU), which
presented its innovative “Silicon Bio-FET Sensors IC and Platform for Biomarker Detection” at
booth N327A. The platform attracted significant attention from both academia and industry for its
ultra-high sensitivity and modular design.
The team successfully fabricated stable, high-quality sensing devices using mature semiconductor
processes across two foundries and three manufacturing technologies. Demonstrated applications
covered a wide spectrum of biomarkers, including DNA, RNA, proteins, viruses, bacteria, cancer
cells, and immune cells. A prototype reader integrated with a microcontroller unit (MCU) was also
developed. Experimental results showed the platform achieved detection sensitivity down to the
attomolar (aM, 10−18 M) level with a broad dynamic range, underscoring its strong potential for
real-world applications.
Prof. Yang emphasized, “By combining semiconductor technology with biosensing technology,
our platform enables rapid, sensitive, and standardized detection at the molecular level. It holds
promise for point-of-care testing, personalized medicine, and public health surveillance.” Current
demonstrations include precision medicine, early disease diagnostics, food safety testing, and
animal and plant disease detection.
A key advantage of the platform is its full compatibility with existing semiconductor foundry
production lines, requiring no additional process development. This significantly shortens
commercialization timelines while reducing manufacturing costs. In addition, its modular design
allows users to flexibly switch detection targets simply by replacing surface bio-probes, greatly
expanding its versatility.
During the exhibition, Prof. Yang’s team engaged with experts from the biotechnology, medical,
environmental monitoring, and academic sectors, showcasing Taiwan’s latest achievements in
bridging semiconductor technology with biosensing innovation.
For further information or collaboration inquiries, please contact: Dr. Tian-Mu Su
📧 Email: imidase@gmail.com
📞 Phone: 03-5712121#56912
